All open & upcoming SBIR/STTR topics

350 topics, sorted by close date. Source: SBIR.gov, enriched with the DoD Innovation Portal.

5G Signature Tracking Mitigation via Cyber Deception

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSBIROSW26BZ06-NV028

As military and government personnel increasingly rely on commercial mobile networks, the management of digital signatures has become a critical operational concern.

AI/ML for Next Generation of Missile Detection, Warning, Tracking, and Reporting

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BX06-NV510

The purpose of this topic is to address a critical need within the U.S.

Agentic AI Based Cognitive Radar for GEOINT Mission

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSBIROSW26BZ06-DV033

Agentic AI enables autonomous control of expert systems for desired information gathering or completing a task.

Agentic-AI, Schema-Driven Decision Management for Auditable Studies and Acquisition Decisions

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · ARMYSBIRARM26BX06-NV012

This topic will prototype and demonstrate a schema-driven Decision Management (DM) foundation plus a governed agentic AI layer that turns messy decision requests into auditable, signer-ready Decision Packages.

Agentic-AI, Schema-Driven Decision Management for Auditable Studies and Acquisition Decisions

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · ARMYSTTRARM26TX06-NV003

This topic will prototype and demonstrate a schema-driven Decision Management (DM) foundation plus a governed agentic AI layer that turns messy decision requests into auditable, signer-ready Decision Packages.

Architected Energy Dissipation Structures with Tunable Rigid-flexible Behaviors

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSTTROSW26TZ06-NV010

The DoW requires lightweight protection materials for a variety of applications, including personal protection, vehicle safety, and shielding sensitive electronics.

Artificial Intelligence Performance Evaluation Tool

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSTTRDAF26TZ06-NV006

The proposed research effort aims to address critical gaps in the evaluation and validation of Artificial Intelligence (AI) systems within the Air Force by developing an Artificial Intelligence Performance Evaluation Tool.

Automated Combat Assessment at the Edge

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSTTRDAF26TZ06-NV007

Combat assessment (physical and functional) provides tactically relevant information for re-strike and re-planning.

Autonomous On Orbit Logistics and Sustainment Architecture

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BX06-DV513

Space systems today are designed for single use and lack the ability to be maintained, repaired, or resupplied once deployed.

Bio-inspired Underwater Teams

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSTTROSW26TZ06-NV008

Bio-inspired underwater vehicles have nearly matched the speeds and efficiencies of real fish.

Casualty Operations & Resource Prediction Software (CORPS)

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASBIRDPA26BZ06-DV027

The challenges underlying crisis medical response in austere and contested environments are significantly different than those underlying long-range planning or response in established theaters.

Compact Passive Radar

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSBIROSW26BZ06-DV025

In contested A2/AD environments, active radar emissions act as beacons for adversary Electronic Warfare.

Counter Adversial GPS Jamming

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSTTRDAF26TZ06-DV008

Military and commercial missions rely heavily on the Global Positioning System (GPS), but GPS signals, due to their weak intensity and their need to travel considerable distances, are vulnerable to external interference such as jamming and spoofing.

Cyberspace Warfare for Space

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BX06-DV512

The USSF’s defensive cyber operations mission is focused on the rapid integration of capabilities into the Defensive Cyber Warfare (DCW) pipeline to address unique and complex cybersecurity requirements for space systems.

DIRECT TO PHASE II: Minimally Invasive Remote Blood Collection Device for Free-Ranging Cetaceans

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · NAVYSBIRDON26BZ06-DV088

Navy bottlenose dolphins are valuable Fleet assets whose health and well-being are essential to sustaining mine countermeasures, port security, and object recovery missions.

Defect Metrology and Charge Trapping Dynamics in Transfer-Doped Diamond Transistors

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSBIROSW26BZ06-NV026

Hydrogen-terminated (surface-channel) diamond transistors hold great promise for next-generation, high-frequency, high-power RF electronics and advanced communications due to diamond's high breakdown field and superior thermal conductivity.

Design of RoomTemperature THz and Infrared Sensing Devices Using Non-Toxic, Supply-Chain Secure Material Platform

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSTTROSW26TZ06-NV006

Infrared sensing sits at an inflection point.

Development of Ultrafast Nonvolatile Memory Based on Sliding Ferroelectricity in Moiré Polar Homostructures

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSTTROSW26TZ06-NV005

Twisted stacks of van der Waals (vdW) crystals can form moiré superlattices with polar domains whose dipoles are antiferroelectrically aligned and controllable by applied electric fields [1].

Engineered Microstructures for Enhanced IR Aperture Performance

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSBIROSW26BZ06-NV024

The Navy has demonstrated within its laboratories that a composite ceramic exhibiting IR transparency can be produced with distinct phases, microstructural feature sizes below 100 nm in all phases, and porosity content below 0.1% on component parts as large as 0.4 inch in lateral dimension.

Expeditionary Solar Refinery for Direct Synthesis of Methanol Feedstock from Water and Air

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSTTROSW26TZ06-NV009

Modern warfare tactics have demonstrated the need to shift toward small, specialized, dismounted tactical units which can operate free from the supply line.

Flightline Radio Network

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BZ06-NV036

Flight line operations at Edwards Air Force Base (AFB) face increasing demands for more efficient, secure, and real-time communication systems to enhance aircraft maintenance, logistics, and operational performance.

Fuel-Flexible Spacecraft Electric Propulsion System

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASTTRDPA26TZ06-DV005

Spacecraft electric propulsion (EP) systems typically rely on noble gas fuels (xenon, krypton, argon) stored in high pressure tanks.

Ground and Air Launched Drone Swarms Create a Self-Protecting Perimeter Using Autonomous AI

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BX06-DV026

Mobility Air Forces aircraft serve as the logistical backbone of the Department of War and operate as high-value assets in modern contested environments that can be significantly augmented with enhanced organic self-protection and intelligence, surveillance, and reconnaissance capabilities to maintain operational overmatch.

ICU-in-a-Box: Autonomous Extracorporeal Multiple-Organ Support Therapies

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASBIRDPA26BZ06-DV029

Severe hemorrhage is the number one cause of preventable combat deaths, followed by airway compromise (Eastridge, 2012), with increased artillery, thermobaric and incendiary munitions use (Remondelli et al.

Influence Benchmarks for AI Systems

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASBIRDPA26BZ06-DV026

This topic seeks to develop a simulated market as a test environment to characterize the latent behavioral preferences of AI systems.As warfighters increasingly engage with AI systems, particularly agents that rely on large-language models (LLMs), concern has arisen that the systems may encourage cognitive behavior in users that impart hidden biases, impair judgement, and ultimately degrade warfighting capacity.

Localization, Characterization, and Modeling of Freestream Disturbances in Hypersonic Wind Tunnels

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASTTRDPA26TZ06-DV006

Hypersonic ground-test facilities are critical for evaluating aerodynamic forces, aerothermodynamic heating, and boundary-layer transition (BLT) behavior on high-speed flight vehicles.

Low Noise & Low-SWaP High-Repetition Rate Mode-Locked Lasers for High-Speed Photonics

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BZ06-NV034

Mode-locked semiconductor lasers can support high repetition rates up to 100 GHz due to the high gain and fast gain recovery unlike in fiber lasers or doped dielectric gain medium lasers.

Low SWaP-C Tactical Awareness Payload for Proliferated, Agile Satellites (TAPPAS) for Space Domain Awareness

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BX06-DV511

This D2P2 effort is to develop low Size, Weight, Power, and Cost (SWaP-C) technology for an on-board sensing payload to provide local situational awareness.

Low-Cost Multi-Function Ku-Band RF System for Prompt Strike Weapons

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BZ06-DV037

Current multifunction radar systems for use onboard various types of small airborne platforms are prohibitively expensive to procure at scale, and this is especially true for systems engineered for use in demanding high subsonic regimes (peak velocity greater than Mach 3 but under Mach 5).

Monolithic Graphene–CMOS Broadband (UV-LWIR) Focal Plane Arrays for target detection in low-light conditions

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSBIROSW26BZ06-DV027

The Navy continues to field multiple seeker technologies to detect, identify and engage targets in multi-domain operations through obscurants. However, you cannot detect something you cannot see.

New World Screwworm Networked Detection, Identification, and Surveillance System

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASBIRDPA26BZ06-DV024

New World Screwworm (NWS or Cochliomyia hominivorax) larvae infest the living tissue of warm-blooded animals.

Noninvasive Detection and Localization of Occult Hemorrhage

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASBIRDPA26BZ06-DV025

TThe goal of this development effort is to produce a noninvasive or minimally invasive capability that enables Role 1 medical personnel (specifically, a combat medic with no surgical or pre-operative imaging expertise) to rapidly detect, localize, and characterize the rate of life-threatening, occult, or non-compressible torso hemorrhage (NCTH) that cannot be precisely identified through routine clinical assessments available in the field.

Novel Radio Frequency Sensing Technologies

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASBIRDPA26BZ06-DV023

Detecting and mapping deep subsurface mineral deposits typically requires localized or low-altitude operations.

OPEN - Proliferated Low-Altitude Detection for C-sUAS

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BX06-DP027

This DAF focused open topic seeks C-sUAS detect options for transition into the USAF and USSF, specifically supporting AFLCMC/ES and the JIATF 401 marketplace.

Quantum Memory for Secure Communication

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSBIRDAF26BZ06-NV035

The rapid advancement of quantum computing poses a significant challenge to traditional encryption methods, potentially compromising the security of digital communications.

Resilient Integrated Photonic Transport In Denied Environments (RIPTIDE)

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · SOCOMSBIRSOC26BZ06-DV006

Future autonomous operations will occur in contested electromagnetic environments where traditional positioning, navigation, and timing (PNT) references cannot be assumed.

Scalable Hard-mask materials with Improved Etch resistance and Low Degradation for Extreme-aspect-Ratio fabrication (SHIELDER)

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASTTRDPA26TZ06-DV004

Next-generation defense-relevant microsystem technologies, such as 3D integrated circuits, high-density memory arrays, MEMS inertial sensors and RF filters, and integrated photonic devices, rely on the precise manufacturing of extreme high-aspect-ratio features within a chip [1-3].

Scalable Processing of Large Area, Oriented 2-Dimensional Polymer Films

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSTTROSW26TZ06-NV007

2-dimensional polymers (2DPs) such as covalent organic frameworks (COFs) are an emerging class of materials which have displayed significant potential in applications ranging from catalysis, energy storage, dielectrics, nanofiltration, gas storage, and mechanically robust engineering materials.

Smart Manufacturing

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSBIROSW26BZ06-DV032

The realistic near-to-mid-term serviceable addressable market for private 5G among U.S.

Smart Venues and Stadiums

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSBIROSW26BZ06-DV031

The realistic near-to-mid-term serviceable addressable market for private 5G/6G-ready platforms among U.S.

Space Domain Operational Environment Assessment

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · USAFSTTRDAF26TX06-NV514

With the acknowledgement of space as a warfighting domain in 2019, the U.S. Space Command was established as a geographic combatant command.

TRIAGE-X: Autonomous Casualty Triage and Treatment in Chemically Contaminated Mass Casualty Events

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · DARPASBIRDPA26BZ06-DV028

DARPA seeks innovative approaches to autonomous chemical, biological, radioactive, and nuclear (CBRN) triage that measurably improve casualty survival and increase the effective capacity of a medical response during CBRN disasters.

Telecom Band Geometric Amplifier

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSTTROSW26TZ06-NV004

Present-day devices for amplifying telecom laser light mostly produce gain by incoherently pumping a medium (optically or electrically), or by coherently pumping a nonlinear medium with a laser.

Vision Language Model (VLM) for Synthetic Aperture Radar (SAR) target search and classification from Sensor Independent Complex Data (SICD)

Closes Oct 21, 2026 · 8d leftDepartment of War (DoD) · OSDSBIROSW26BZ06-DV034

Vision language models (VLMs) combine multimodal (Video, SAR and Infrared Imagery) data/imagery and generative AI models to understand and process video, image, and text.

AIR QUALITY

Closes Nov 8, 2026 · 26d leftEnvironmental Protection AgencySBIR2

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CIRCULAR ECONOMY/SUSTAINABLE MATERIALS

Closes Nov 8, 2026 · 26d leftEnvironmental Protection AgencySBIR3

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CLEAN AND SAFE WATER

Closes Nov 8, 2026 · 26d leftEnvironmental Protection AgencySBIR1

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SAFER CHEMICALS

Closes Nov 8, 2026 · 26d leftEnvironmental Protection AgencySBIR4

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AI-Enabled Computed Vision Air-to-Air Refueling Performance Assessment and Automated Pilot Debrief System

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSTTRDAF27TZ01-DV001

Air-to-air refueling (AAR) is a critical Department of the Air Force and Department of the Navy capability enabling global mobility, long-range strike, combat airpower projection, and sustained aviation operations.

Advanced Reserve Power Source Technologies

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-DV013

Power source performance in terms of power and energy density is the major objective with affordability, safety, and reliability secondary objectives of Air Force Armament Directorate programs for advanced reserve power sources for weapon systems.

Agile Autonomous Technical Data Package to Path Robotic Task Specification

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-DV012

Here is a draft for a Direct to Phase II SBIR solicitation topic based on the technical capabilities of the data extraction and automated path-planning pipeline.

Agile Wire Harness Manipulation and Installation for Unmanned Aerial Systems

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-DV011

Context & BackgroundModern Department of Defense (DoD) manufacturing and depot sustainment environments increasingly depend on agile automation to scale up production and maintain rapid operational readiness.

Cleaner for the Time Domain Reflectometer Tank Level Indicator

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · NAVYSBIRDON27BZ01-NV001

Fouling on the TDR sensor used for TLI is a persistent problem. The TDR is necessary to provide accurate and precise readings for fuel measurement.

Counter-Unmanned Aerial Systems Rapid Maturation

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · OSDSBIROSW27BZ01-NV001

Inexpensive, highly maneuverable, commercially available unmanned aerial systems (UAS) threaten tactical forces, critical infrastructure, and installations.

Counter-Unmanned Aerial Systems Rapid Maturation

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · OSDSBIROSW27BZ01-DV002

Inexpensive, highly maneuverable, commercially available unmanned aerial systems (UAS) threaten tactical forces, critical infrastructure, and installations.

Cyber Resiliency for Fog and Edge Computing Devices

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSTTRDAF27TZ01-DV002

This topic is intended for technology proven ready to move directly into a Phase II. Therefore, a Phase I award is not required.

Fire Resistant Joiner Bulkhead

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · NAVYSBIRDON27BZ01-NV002

Fire represents a grave hazard to Navy vessels.

Fusion of Cooperative Information Sharing for Uncrewed Air Systems (FOCISAUS)

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSTTRDAF27TZ01-DV003

Distributed air operations increasingly depend on timely awareness of objects, hazards, and activities beyond the field of view of any individual platform.

G-TEAD USAREUR-AF ACE 27-02: Spectrum Enabled Warfare Powered by xTech

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · ARMYSBIRARM27BX01-DP001

The operational challenge on the Eastern Flank is the enablement of U.S.

High Speed, Low Temperature Hyperspectral Imager for High Enthalpy Ground Testing

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-NV006

AEDC requires a method to resolve temperature and emissivity across the surface of test articles.

Input-Output Unit (IOU) for Secure Processing and Routing of Hull, Mechanical, & Electrical (HM&E) and Navigation Signals

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · NAVYSBIRDON27BZ01-NV004

IOUs are used on all Navy DDG 51 class ships to transfer Steering Control, Machinery Control, and Damage Control signals, as well as Interior Communication Alarm and Indication, Synchro and Digital Navigation data.

Intermediate Temperature Cooling Unit

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · NAVYSBIRDON27BZ01-NV005

Navy ships have a chilled water system that runs throughout the ship providing cooling to electronic equipment.

Long Rod Delivery System

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-NV004

The lack of a non-destructive, high-precision launching method for high length-to-diameter (L/D) projectiles fundamentally degrades the fidelity of Live Fire Test and Evaluation (LFT&E) data.

Low SWaP, 2-micron Fiber Amplifiers

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-DV010

High-power fiber lasers operating in the 2-micron regime offer critical advantages for defense, medical, and industrial applications, including eye-safer directed energy, advanced sensing, and precision materials processing.

Multiple Telemetry Site Signal Source Synchronization

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-NV003

Flight test missions that traverse multiple Test Ranges (e.g. hypersonic vehicles/weapons, cruise missiles, long-range weapon systems etc.) or that require different test support infrastructures (e.g.

ONR Open Topic for Low-Cost Heads Up Displays (HUDs) for Virtual & Augmented Reality (VR/AR)

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · NAVYSBIRDON27BX01-NP001

ONR requests proposals for existing technology demonstration platforms, prototypes, and commercial products that provide domestically-sourced, low-cost HUDs) for first-person view (FPV) drone pilots, and augmented reality (AR) capabilities for Forward Observers (FOs) and Joint Terminal Air Controllers (JTACs).

Optimally Packaged Assembly for Laser Systems (OPALS)

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-NV002

The Air Force requires light weight, compactly packaged optical systems to perform critical beam control functions for airborne high energy laser systems.

Reusable Illumination System

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-DV007

The PF300 flash bulbs, that provide high-intensity illumination for high-speed video acquisition, are no longer in production.

Shallow Jet Spurt Engineering Model

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-NV001

This topic seeks the development of a computationally efficient engineering-level model to predict the formation and characteristics of the "spurt" in fluid cavity created jets.

Technical Data Package Modernization for Information Assurance and Secure Data Exchange

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-DV008

Background and Problem Statement: The modernization of Technical Data Packages (TDPs) is imperative to address the Air and Space Force’s operational challenges in securely managing large-scale, complex datasets associated with advanced platforms and their sustainment life cycles.

US Production of Ultra-High Temperature Ceramic-Yielding Preceramic Polymers

Closes Nov 25, 2026 · 43d leftDepartment of War (DoD) · USAFSBIRDAF27BZ01-DV009

The scaled production of C/C-UHTCs composites (UHTCMCs) for defense applications requires the manufacturing of UHTC precursors in quantities sufficient to support acquisition programs.

NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)

Closes Apr 6, 2027 · 175d leftHealth and Human Services (NIH, ARPA-H, CDC…) · NIHSBIRPA-27-101

Background The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs (also known as America's Seed Fund) are major sources of early-stage funding for U.S.

NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

Closes Apr 6, 2027 · 175d leftHealth and Human Services (NIH, ARPA-H, CDC…)STTRPA-27-102

Background The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs (also known as America's Seed Fund) are major sources of early-stage funding for U.S.

NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

Closes Apr 6, 2027 · 175d leftHealth and Human Services (NIH, ARPA-H, CDC…)SBIRPA-27-100

Background The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs (also known as America's Seed Fund) are major sources of early-stage funding for U.S.

SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

Closes Apr 6, 2027 · 175d leftHealth and Human Services (NIH, ARPA-H, CDC…)SBIRPAR-27-098

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs (also known as America's Seed Fund) are major sources of early-stage funding for U.S.

Accessible and Inclusive AR/VR/MR

Closes Jul 7, 2027 · 267d leftNational Science FoundationAV1

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Advanced Engineering Materials

Closes Jul 7, 2027 · 267d leftNational Science FoundationAM1

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Advanced Inclusive Learning Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationLC1

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Advanced Manufacturing

Closes Jul 7, 2027 · 267d leftNational Science FoundationM

The Advanced Manufacturing topic aims to support emerging innovations in manufacturing with the potential to stimulate the nation's manufacturing sector by improving efficiency, competitiveness and sustainability.

Advanced Materials

Closes Jul 7, 2027 · 267d leftNational Science FoundationAM

The Advanced Materials topic addresses the development of new and improved materials for a wide variety of commercial and industrial applications.

Advanced Metrology and Sensors

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH1

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Advanced Nuclear Energy Tech

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN1

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Advanced Optical Components and Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH2

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Advanced Systems for Scalable Analytics

Closes Jul 7, 2027 · 267d leftNational Science FoundationAA

The Advanced Systems for Scalable Analytics topic focuses on innovations needed for building systems that organize and process large and ever-increasing volumes of structured, semi-structured and unstructured data to reveal actionable new insights.

Agricultural Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG

The Agricultural Technologies topic supports innovations enabling farm production ecosystems that support the proper utilization of natural resources.

Agroforestry

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG1

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Algorithms and Applications

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH1

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Animal Biotechnology

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT1

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Aquaculture

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT2

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Artificial Intelligence

Closes Jul 7, 2027 · 267d leftNational Science FoundationAI

The Artificial Intelligence topic focuses on cutting-edge technologies in the field of deep learning-based AI systems and AI-based hardware.

Assistive, Enabling and Rehabilitative technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationDH1

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Augmented Virtual and Mixed Reality

Closes Jul 7, 2027 · 267d leftNational Science FoundationAV/VR/MR

The Augmented Virtual and Mixed Reality (AR/VR/MR) topic focuses on advancing immersive technological experiences for humans grounded in research.

Autonomous Systems and Economies, and Smart Contracts

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL1

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Aviation

Closes Jul 7, 2027 · 267d leftNational Science FoundationMO1

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Behavioral Transitions

Closes Jul 7, 2027 · 267d leftNational Science FoundationMO2

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Bio-Inspired Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT3

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Biochemicals

Closes Jul 7, 2027 · 267d leftNational Science FoundationCT1

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Bioinstruments and Biosensors

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT4

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Biological Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT

The Biological Technologies topic covers a wide range of technology areas to advance engineering and science innovation across the biological spectrum.

Biomedical Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationBM

The Biomedical Technologies topic aims to support the early-stage development of novel products, processes or services that will enable the delivery of high-quality, economically efficient healthcare.

Blockchain, DAGs, and Next-Gen Protocols

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL2

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Building Analytical System for Learning from Dynamic Environments

Closes Jul 7, 2027 · 267d leftNational Science FoundationAA1

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Building and Infrastructure

Closes Jul 7, 2027 · 267d leftNational Science FoundationM1

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CO2 and Methane Conversion, Petrochemicals, Oil and Gas

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN2

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Carbon Sequestration

Closes Jul 7, 2027 · 267d leftNational Science FoundationM2

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Catalysts, Advanced Chemicals and Materials

Closes Jul 7, 2027 · 267d leftNational Science FoundationCT2

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Cell and Tissue Engineering

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT5

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Chemical Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationCT

The Chemical Technologies topic covers a wide range of technology areas of current and emerging commercial significance to many areas, including the broad chemical industry; food processing and technology; agrochemicals; chemical alternatives and organics; green chemicals; water treatment and separations; advanced catalysts and materials; and biochemicals.

Chemical and Environmental Sensing and Data

Closes Jul 7, 2027 · 267d leftNational Science FoundationCT3

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Climate Change Adaptation, Mitigation and Reversal

Closes Jul 7, 2027 · 267d leftNational Science FoundationET1

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Cloud and High-Performance Computing

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH

The Cloud and High-Performance Computing (HPC) topic focuses on innovations that result in substantial improvements to cloud computing or high-performance computing platforms.

Coatings and Surface Modifications

Closes Jul 7, 2027 · 267d leftNational Science FoundationAM2

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Cognitive Science-based Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAI1

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Communication and Networking Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationW1

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Communications, Information, and Data Storage

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH3

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Computation on Encrypted Data

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA1

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Computational Architecture

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH2

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Computer Vision Based AI Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAI2

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Convergence of AI and Cloud/HPC

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH3

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Convergence with Big Data, and Artificial Intelligence

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL3

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Convergence with Internet of Things, Crowdsourcing and Crowdsensing

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL4

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Conversational AI Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAI3

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Cryptography, Security, and Cybersecurity

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL5

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Cryptography, including Post-quantum Cryptography

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA2

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Cybermanufacturing

Closes Jul 7, 2027 · 267d leftNational Science FoundationM3

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Cybersecurity and Authentication

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA

The Cybersecurity and Authentication topic focuses on innovations related to the security and integrity of data and data processing and the authentication of people and devices.

Data Mining, Machine Learning (Non-deep learning-based), and Reinforcement Learning

Closes Jul 7, 2027 · 267d leftNational Science FoundationAA2

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Data Privacy and Integrity

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA3

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Data and communication

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP4

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Decision Support and Optimization

Closes Jul 7, 2027 · 267d leftNational Science FoundationAA3

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Device Authentication

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA4

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Diagnostics

Closes Jul 7, 2027 · 267d leftNational Science FoundationBM1

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Digital Assets

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL6

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Digital Ecosystem for the Environment

Closes Jul 7, 2027 · 267d leftNational Science FoundationET2

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Digital Health

Closes Jul 7, 2027 · 267d leftNational Science FoundationDH

The Digital Health topic aims to support the early-stage development of novel devices, components, systems, algorithms, networks, applications or services that will enable the transformation of healthcare from reactive, hospital-centered and indemnity-based to proactive, person-centered, preventive and cost-efficient.

Directed Energy

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN3

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Distributed Consensus and Fault Tolerance Mechanisms

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL7

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Distributed Ledger

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL

The Distributed Ledger topic area covers a wide range of technology areas of current and emerging commercial significance and impact spanning all areas of distributed ledgers, including blockchains, directed acyclic graphs (DAGs) and related capabilities (cryptography, smart contracts, etc.).

Distributed Ledger

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA5

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Distributed Ledger Interoperability

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL9

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Distributed Ledger in Edge and Cloud Computing

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL8

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Distributed Ledger in Network Architecture and Management

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL10

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Distributed Manufacturing

Closes Jul 7, 2027 · 267d leftNational Science FoundationM4

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Drug Delivery Methods

Closes Jul 7, 2027 · 267d leftNational Science FoundationBM2

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Drug Discovery

Closes Jul 7, 2027 · 267d leftNational Science FoundationPT1

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Ecomanufacturing

Closes Jul 7, 2027 · 267d leftNational Science FoundationM5

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Edge Computing

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH4

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Electromagnetics

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN4

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Electronic Devices

Closes Jul 7, 2027 · 267d leftNational Science FoundationS1

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Electronic Materials

Closes Jul 7, 2027 · 267d leftNational Science FoundationS2

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Emission or Waste Reduction and the Circular Economy

Closes Jul 7, 2027 · 267d leftNational Science FoundationET3

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Encryption, including Homomorphic Encryption

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA6

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Energy Efficiencies and Data Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN5

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Energy Efficiency and Sustainability

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH5

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Energy Harvesting Devices and Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationPM1

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Energy Production and Power Generation

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN6

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Energy Storage

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN7

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Energy Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN

The Energy Technologies topic covers new energy sources and resources, power generation, energy storage and electronic systems for energy sources used in mobile technologies and off-grid applications.

Enhanced UI/UX for Immersive AR/VR/MR

Closes Jul 7, 2027 · 267d leftNational Science FoundationAV2

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Environmental Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationET

Environmental Technologies cover a range of innovations focused on sustainability, high commercial impacts and societal and environmental benefits.

Environmental Technologies for Achieving Sustainable Development

Closes Jul 7, 2027 · 267d leftNational Science FoundationET5

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Environmental and Societal Impact Measurement

Closes Jul 7, 2027 · 267d leftNational Science FoundationET4

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Environmentally Sustainable Solutions for AR/VR/MR Design

Closes Jul 7, 2027 · 267d leftNational Science FoundationAV3

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Ethical AI Frameworks for Advancing Education

Closes Jul 7, 2027 · 267d leftNational Science FoundationLC2

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Farming in Underserved Communities

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG2

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Fermentation

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT6

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Financial Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL11

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Food Processing, Chemicals and Agriculture

Closes Jul 7, 2027 · 267d leftNational Science FoundationCT4

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Food Waste Mitigation

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG3

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Food, Regenerative Agriculture, and Energy

Closes Jul 7, 2027 · 267d leftNational Science FoundationET6

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Fusion

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN8

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General Medical Devices

Closes Jul 7, 2027 · 267d leftNational Science FoundationMD1

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Green Chemicals and Chemical Alternatives

Closes Jul 7, 2027 · 267d leftNational Science FoundationCT5

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HCI to Enhance Human Cognitive Capacity

Closes Jul 7, 2027 · 267d leftNational Science FoundationHC1

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Habitat Conservation, Adaptation and Restoration

Closes Jul 7, 2027 · 267d leftNational Science FoundationET7

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Harvesting Complex Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG4

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Health and Biomedical informatics

Closes Jul 7, 2027 · 267d leftNational Science FoundationDH2

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Health in Underserved Communities

Closes Jul 7, 2027 · 267d leftNational Science FoundationBM3

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Health in Underserved Communities

Closes Jul 7, 2027 · 267d leftNational Science FoundationDH3

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Healthcare Workflow, Economics and Delivery

Closes Jul 7, 2027 · 267d leftNational Science FoundationDH4

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Human Assistive Technologies and Bio-related Robotics

Closes Jul 7, 2027 · 267d leftNational Science FoundationR1

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Human viability and sustainability

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP6

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Human-Centric AR/VR/MR Analytics for Collaboration

Closes Jul 7, 2027 · 267d leftNational Science FoundationAV4

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Human-Computer Interaction

Closes Jul 7, 2027 · 267d leftNational Science FoundationHC

The Human-Computer Interaction (HCI) topic aims to bridge the gap between research-based innovation and practical applications by catalyzing high-risk advancements rooted in research.

Human-Machine Interfaces and Control/Architecture

Closes Jul 7, 2027 · 267d leftNational Science FoundationR2

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Human-to-Technology Interfaces and Decentralized Applications (dApps)

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL12

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Hydrogen Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN9

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Hypersonic

Closes Jul 7, 2027 · 267d leftNational Science FoundationMO3

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Immersive AR/VR/MR Fostering Shared Experiences

Closes Jul 7, 2027 · 267d leftNational Science FoundationAV5

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Implantables or Procedures

Closes Jul 7, 2027 · 267d leftNational Science FoundationMD2

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

Improved Resilience through Interspecies Interchange

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG5

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In space services and production

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP5

SBIR.gov lists this topic without a description. Open the official solicitation for the full scope.

In-memory Processing

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH6

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Infrastructure and Flow

Closes Jul 7, 2027 · 267d leftNational Science FoundationMO4

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Instrumentation and Hardware Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationIH

The Instrumentation and Hardware Systems topic addresses the research and development of new and improved instrumentation and related systems for a wide variety of commercial and industrial applications.

Instrumentation or Hardware Systems for Actuation, Control, and Manipulation

Closes Jul 7, 2027 · 267d leftNational Science FoundationIH1

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Instrumentation or Hardware Systems for Detection and Characterization

Closes Jul 7, 2027 · 267d leftNational Science FoundationIH2

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Instrumentation or Hardware Systems for Imaging

Closes Jul 7, 2027 · 267d leftNational Science FoundationIH3

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Integrated Circuit Design

Closes Jul 7, 2027 · 267d leftNational Science FoundationS3

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Interconnects

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH7

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Internet of Things

Closes Jul 7, 2027 · 267d leftNational Science FoundationI

The Internet of Things (IoT) is a rapidly evolving field that involves the interconnection and interaction of smart objects (objects or devices with embedded sensors, onboard data processing capability, and a means of communication) to provide automated services that would otherwise not be possible.

IoT Communications

Closes Jul 7, 2027 · 267d leftNational Science FoundationI1

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IoT Integrated Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationI2

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IoT Sensors and Actuators

Closes Jul 7, 2027 · 267d leftNational Science FoundationI3

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Knowledge and Data Management Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAA4

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Language-Based AI Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAI4

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Launch vehicles and propulsion

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP1

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Learning and Cognition Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationLC

Innovative approaches to learning and cognition development leverage groundbreaking technological advancements rooted in research.

Life Science Research Tools

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT7

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Lighting and Displays

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH4

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Marine

Closes Jul 7, 2027 · 267d leftNational Science FoundationMO5

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Marketplaces for Data and Models

Closes Jul 7, 2027 · 267d leftNational Science FoundationAA5

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Materials and Devices for Power Electronics

Closes Jul 7, 2027 · 267d leftNational Science FoundationPM2

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Materials and Devices for Thermal Management

Closes Jul 7, 2027 · 267d leftNational Science FoundationPM3

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Materials for Biomedical Applications

Closes Jul 7, 2027 · 267d leftNational Science FoundationBM4

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Materials, Processes, Prototyping Methods or Enablers

Closes Jul 7, 2027 · 267d leftNational Science FoundationMD3

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Medical Devices

Closes Jul 7, 2027 · 267d leftNational Science FoundationMD

The Medical Devices topic aims to develop novel medical device platforms, introduce innovative medical technologies or translate emerging scientific principles into health practice.

Medical Diagnostics and Devices

Closes Jul 7, 2027 · 267d leftNational Science FoundationDH5

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Medical Imaging

Closes Jul 7, 2027 · 267d leftNational Science FoundationBM5

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Metals and Ceramics

Closes Jul 7, 2027 · 267d leftNational Science FoundationAM3

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Microbiome and Microbial Diversity

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT8

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Microelectronics Packaging and Systems Integration

Closes Jul 7, 2027 · 267d leftNational Science FoundationS4

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Middleware

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH8

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Mobility

Closes Jul 7, 2027 · 267d leftNational Science FoundationMO

The Mobility topic encourages novel innovations in the land, air, and sea-based movement of goods and people that improve sustainability and resiliency.

Modeling and Simulation

Closes Jul 7, 2027 · 267d leftNational Science FoundationM6

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Monitoring Devices

Closes Jul 7, 2027 · 267d leftNational Science FoundationBM6

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Monitoring or Instrumentation

Closes Jul 7, 2027 · 267d leftNational Science FoundationMD4

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Nanotechnology

Closes Jul 7, 2027 · 267d leftNational Science FoundationN

The Nanotechnology topic addresses the creation and manipulation of functional materials, devices and systems with novel properties that are achieved through the control of matter at a submicroscopic scale (from a fraction of nanometer to about 100 nanometers).

Nanotechnology

Closes Jul 7, 2027 · 267d leftNational Science FoundationN1

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Natural Resources and Critical Minerals

Closes Jul 7, 2027 · 267d leftNational Science FoundationM7

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Nature-based Solutions

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG6

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Network and Device Security

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA7

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Networked Sensors and Sensing

Closes Jul 7, 2027 · 267d leftNational Science FoundationW2

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Networking

Closes Jul 7, 2027 · 267d leftNational Science FoundationI4

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Neuroadaptive Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationHC2

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Novel AI Hardware Technologies (e.g.: Neuromorphic Computing, High-performance Technologies for AI, Smart and Secure Edge Devices, etc.)

Closes Jul 7, 2027 · 267d leftNational Science FoundationAI5

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Novel Advanced Materials-based Sensors

Closes Jul 7, 2027 · 267d leftNational Science FoundationAM4

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Novel Power and Thermal Management Sensors

Closes Jul 7, 2027 · 267d leftNational Science FoundationPM4

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Novel Semiconductor-based Sensors

Closes Jul 7, 2027 · 267d leftNational Science FoundationS5

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Novel Visualization Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAA6

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Other Advanced Materials Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAM6

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Other Agricultural Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG10

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Other Augmented Virtual and Mixed Reality Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAV6

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Other Biological Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT11

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Other Biomedical Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationBM8

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Other Chemical Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationCT7

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Other Cloud and High-Performance Computing Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH13

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Other Cybersecurity and Authentication Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA12

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Other Digital Health Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationDH7

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Other Distributed Ledger Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL15

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Other Energy Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN11

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Other Environmental Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationET11

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Other Human-Computer Interaction Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationHC5

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Other Instrumentation or Hardware Systems Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationIH4

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Other IoT Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationI5

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Other Learning and Cognition Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationLC6

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Other Manufacturing Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationM10

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Other Mobility Topics

Closes Jul 7, 2027 · 267d leftNational Science FoundationMO8

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Other Novel Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAI8

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Other Novel Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationAA8

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Other Pharmaceutical Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationPT3

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Other Photonics Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH11

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Other Power Management Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationPM8

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Other Quantum Information Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationQT6

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Other Robotics Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationR6

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Other Semiconductor Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationS9

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Other Space-related Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP12

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Other Topics

Closes Jul 7, 2027 · 267d leftNational Science FoundationOT1

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Other Topics

Closes Jul 7, 2027 · 267d leftNational Science FoundationOT

For projects that do not seem to fit into one of the other technology topic areas, but still meet the NSF SBIR/STTR goals of supporting research and development of deep technology with commercial viability and the potential to benefit society, please pick Other Topics and subtopic OT1.

Other Wireless Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationW5

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Performance Monitoring

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH9

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Personal Authentication

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA8

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Personal Transportation

Closes Jul 7, 2027 · 267d leftNational Science FoundationMO6

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Pharmaceutical Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationPT

The Pharmaceutical Technologies topic covers a wide range of technology areas that advance the discovery, formulation, and manufacture of novel drugs, moieties, compounds, products, processes, platforms or services that will improve the selection, quality or price of pharmaceutical and biologic therapies.

Pharmaceutical and Biologic Manufacturing

Closes Jul 7, 2027 · 267d leftNational Science FoundationPT2

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Photonic Devices

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH5

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Photonic Energy Conversion

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH6

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Photonic Materials

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH7

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Photonic Metamaterials and Plasmonics

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH8

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Photonics

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH

The Photonics topic addresses the research and development of new materials, devices, components, and systems that have the potential for revolutionary change in the optics and photonics industries.

Physical, Mental and Behavioral Health

Closes Jul 7, 2027 · 267d leftNational Science FoundationDH6

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Plant Biotechnology

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT9

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Polyculture Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG7

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Power Electronics Circuits and Control Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationPM5

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Power Management

Closes Jul 7, 2027 · 267d leftNational Science FoundationPM

The Power Management topic address the development of novel technologies that enable new power and thermal management solutions.

Power Management Infrastructure and Smart Grid Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationPM6

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Precision Agriculture

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG8

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Processing and Metrology Technology

Closes Jul 7, 2027 · 267d leftNational Science FoundationS6

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Processing on Encrypted Data

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH10

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Processor Architecture and Design

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH11

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Quantum Algorithms

Closes Jul 7, 2027 · 267d leftNational Science FoundationQT1

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Quantum Communications

Closes Jul 7, 2027 · 267d leftNational Science FoundationQT2

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Quantum Computing

Closes Jul 7, 2027 · 267d leftNational Science FoundationQT3

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Quantum Device Manufacturing

Closes Jul 7, 2027 · 267d leftNational Science FoundationM8

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Quantum Information Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationQT

This topic focuses on innovations in information and communications technologies that rely fundamentally on quantum mechanical properties and interactions.

Quantum Optics and Nanophotonics

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH9

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Quantum Sensing and Metrology

Closes Jul 7, 2027 · 267d leftNational Science FoundationQT4

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Quantum Simulation

Closes Jul 7, 2027 · 267d leftNational Science FoundationQT5

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Rehabilitation

Closes Jul 7, 2027 · 267d leftNational Science FoundationMD5

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Renewable Energy Generation & Storage

Closes Jul 7, 2027 · 267d leftNational Science FoundationEN10

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Research-based Design for Behavioral Health

Closes Jul 7, 2027 · 267d leftNational Science FoundationLC3

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Resilience and Resource Management

Closes Jul 7, 2027 · 267d leftNational Science FoundationCH12

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Resiliency and Sustainability

Closes Jul 7, 2027 · 267d leftNational Science FoundationMO7

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Resilient Supply & Distribution

Closes Jul 7, 2027 · 267d leftNational Science FoundationAG9

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Robotic Applications

Closes Jul 7, 2027 · 267d leftNational Science FoundationR3

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Robotics

Closes Jul 7, 2027 · 267d leftNational Science FoundationR

The Robotics topic covers robot intelligence and experiential learning, particularly in the areas of high-performance processors or hardware that provides situational awareness and improved artificial intelligence.

Robotics in Agile Manufacturing, and Co-Robots

Closes Jul 7, 2027 · 267d leftNational Science FoundationR4

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Satellite technology

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP2

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Scalability Solutions and Accumulators

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL13

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Secure Machine-to-Machine Communication

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA10

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Secure and Trusted Computing

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA9

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Security of Cloud and High Performance Computing (HPC) Platforms

Closes Jul 7, 2027 · 267d leftNational Science FoundationCA11

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Semiconductors

Closes Jul 7, 2027 · 267d leftNational Science FoundationS

The Semiconductors topic addresses the research and development of new designs, materials, devices and manufacturing systems that have the potential for impactful change in the semiconductor and microelectronics industry.

Separations and Water Treatment

Closes Jul 7, 2027 · 267d leftNational Science FoundationCT6

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Silicon Photonics and Photonic Integrated Circuits

Closes Jul 7, 2027 · 267d leftNational Science FoundationPH10

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Smart Integrated Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationHC3

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Social and Behavioral Science Based Environmental Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationET8

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Software Technologies for Scalable Analytical Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationAA7

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Space

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP

The Space topic seeks transformative technologies to create solutions for sustainable space exploration, habitation or industrialization that could also have a positive impact on human lives.

Space Transportation and Access

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP10

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Spaceflight infrastructure

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP3

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Structural and Infrastructural Materials

Closes Jul 7, 2027 · 267d leftNational Science FoundationAM5

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Sustainable AI Technologies for Low Resource Environments

Closes Jul 7, 2027 · 267d leftNational Science FoundationAI6

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Sustainable Chemical Manufacturing

Closes Jul 7, 2027 · 267d leftNational Science FoundationM9

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Sustainable Community Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationET9

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Sustainable Education Models for Future Generations

Closes Jul 7, 2027 · 267d leftNational Science FoundationLC4

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Sustainable HCI Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationHC4

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Sustainable Semiconductor Manufacturing

Closes Jul 7, 2027 · 267d leftNational Science FoundationS7

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Synthetic Biology and Metabolic Engineering

Closes Jul 7, 2027 · 267d leftNational Science FoundationBT10

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Systems for Thermal Management

Closes Jul 7, 2027 · 267d leftNational Science FoundationPM7

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Technologies for Trustworthy AI (safe, fair, transparent, privacy-preserving, explainable, and/or secure)

Closes Jul 7, 2027 · 267d leftNational Science FoundationAI7

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Telecommunications Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationSP11

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Tools for Critical Information Analysis to Broaden Engagement

Closes Jul 7, 2027 · 267d leftNational Science FoundationLC5

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Trusted Identity and Identity Management

Closes Jul 7, 2027 · 267d leftNational Science FoundationDL14

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Underground or Underwater Robotics for Low-Visibility, Poor-Connectivity or Hidden Topography

Closes Jul 7, 2027 · 267d leftNational Science FoundationR5

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Water Treatment, Resilience, and Sanitation

Closes Jul 7, 2027 · 267d leftNational Science FoundationET10

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Wearables and External Sensors

Closes Jul 7, 2027 · 267d leftNational Science FoundationMD6

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Wide Bandgap Power Devices and Materials

Closes Jul 7, 2027 · 267d leftNational Science FoundationS8

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Wireless Devices and Components

Closes Jul 7, 2027 · 267d leftNational Science FoundationW3

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Wireless Systems

Closes Jul 7, 2027 · 267d leftNational Science FoundationW4

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Wireless Technologies

Closes Jul 7, 2027 · 267d leftNational Science FoundationW

The Wireless topic involves next-generation wireless communication technologies requiring systems with high data rates, low costs and that support a wide variety of applications and services while maintaining full mobility, minimum latency, and long battery life.

Women's Health

Closes Jul 7, 2027 · 267d leftNational Science FoundationBM7

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Women's Health

Closes Jul 7, 2027 · 267d leftNational Science FoundationMD7

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ARPA-H Lineage Topic

Closes Sep 30, 2027 · 352d leftHealth and Human Services (NIH, ARPA-H, CDC…) · ARPA-HARPA-H 05

he purpose of this topic supports the advancement, commercialization, and translation of technologies that originated from ARPA-H funded efforts.

Breaking Ground: The First Curative, Durable, Non-Surgical Therapy for Endometriosis

Closes Sep 30, 2027 · 352d leftHealth and Human Services (NIH, ARPA-H, CDC…) · ARPA-HARPA-H 04

The purpose of this topic aims to develop treatments for endometriosis that are non-surgical.

Development of an annual test to inform women about their future fertility

Closes Sep 30, 2027 · 352d leftHealth and Human Services (NIH, ARPA-H, CDC…) · ARPA-HARPA-H 01

Development of an annual test to inform women about their future fertility - The purpose of this topic is to discover new biomarkers that provide women with actionable data for fertility planning.

Rapid Comprehensive Diagnostic Test for Multi-System Autoimmune Disease

Closes Sep 30, 2027 · 352d leftHealth and Human Services (NIH, ARPA-H, CDC…) · ARPA-HARPA-H 06

The purpose of this topic is to spur the development of novel, rapid diagnostic assays for multi-system autoimmune disease, which represents an unmet healthcare need.

Universal Platform for Living Adaptive Toxin-removal (UNI-PLAT)

Closes Sep 30, 2027 · 352d leftHealth and Human Services (NIH, ARPA-H, CDC…) · ARPA-HARPA-H 03

The purpose of this topic area is to catalyze the development of a universal, “plug-and-play” synthetic biology platform that enables next-generation microbial chassis capable of performing a broad array of programmable functions.

Versatile Bioadhesives

Closes Sep 30, 2027 · 352d leftHealth and Human Services (NIH, ARPA-H, CDC…) · ARPA-HARPA-H 02

The purpose of this topic is to develop next-generation bioadhesive platforms that can safely and reliably seal, bond, and repair a wide range of tissues in challenging clinical conditions, including wet, bloody, and mechanically dynamic environments.

Virtual Human Brain for the Development of Neurosurgical Robotics

Closes Sep 30, 2027 · 352d leftHealth and Human Services (NIH, ARPA-H, CDC…) · ARPA-HARPA-H 07

The purpose of this topic aims to take a first step toward AI-assisted intracranial microsurgery by creating a high-resolution, physically and anatomically accurate virtual human brain.